
A Vital Diagnostic Tool in Nephrology
At Dr KHOSHA PATEL
As a nephrologist, one of the most powerful tools we have to diagnose kidney diseases is the renal biopsy. This procedure helps determining the cause of kidney dysfunction, guiding treatment decisions, and predicting outcomes. Dr Kosha Patel the best Nephrologist in Ahmedabad at her clinic provides the service of kindey biopsy and experienced with the procedure. However, as with any medical procedure, it’s important to understand when it’s necessary, how it’s performed, and the potential risks involved.

What is a Renal Biopsy?
A renal biopsy involves taking a small sample of kidney tissue with the help of a permanent or a disposable needle for analysis under a microscope. The tissue is examined for signs of damage, inflammation, infection, or other abnormalities. This helps in diagnosing conditions such as glomerulonephritis, lupus nephritis, diabetic nephropathy, and Nephrotic state
AT DR KOSHA PATEL
When is a Renal Biopsy Needed?
When is a Renal Biopsy Needed?
Unexplained kidney dysfunction
If blood or urine tests show abnormal kidney function (elevated creatinine, proteinuria, presence of blood cells in urine )a biopsy may help determine the underlying cause.
Diagnosis of specific kidney diseases
Certain kidney diseases can only be definitively diagnosed through a biopsy.
Monitoring disease progression
A biopsy can help assess the severity of damage in chronic kidney conditions and determine whether treatment is effective and wether the damage is reversible or not.
The Procedure
Renal biopsies are usually performed using a percutaneous approach, which means inserting a needle through the skin to obtain the tissue sample. This is typically done under local anesthesia, and with the guidance of ultrasound to locate the kidney accurately under the guidance of our kidney specialist in Ahmedabad Dr Kosha Patel.
In a small number of cases, the procedure might be done using a transjugular biopsy, where a catheter is inserted through a vein in the neck to reach the kidney. This method is typically used when there are complications like obesity or when the patient has a bleeding disorder

What Happens After a Renal Biopsy?
Renal Biopsy is a day care procedure, After the procedure, patients are typically monitored for several hours in the hospital for any signs of bleeding or discomfort. Most people are able to go home the same day, though some may need to stay overnight for observation. It’s important to avoid heavy lifting and strenuous activity for a week after the biopsy to minimize the risk of complications.
Risks and Complications
While a renal biopsy is generally safe, there are some risks to be aware of, including:

Bleeding
The kidney is a highly vascular organ, so there is a risk of bleeding at the biopsy site. In rare cases, this may require a blood transfusion or further intervention.

Infection
Although rare, infections can occur at the biopsy site.

Pain
Some mild discomfort or pain in the back or abdomen can occur post-procedure, but it usually resolves with pain management.
Interpreting the Results
Once the kidney tissue is collected, it is sent to a pathologist for examination. The pathologist will look for various changes in the tissue, including inflammation, scarring, and the presence of certain immune cells. The biopsy results can provide a definitive diagnosis, such as:
Glomerulonephritis
Chronic kidney disease (CKD)
Nephrotic syndrome
Why choose Dr. Kosha Patel
Why is a Renal Biopsy Important?
A renal biopsy can often reveal the precise cause of kidney dysfunction, allowing for more targeted and effective treatments. For example, certain forms of glomerulonephritis may respond well to immunosuppressive medications, while others might require more aggressive treatments like plasmapheresis. Without a biopsy, it would be difficult to tailor therapy to the specific condition affecting the kidneys.
Moreover, the biopsy results can help predict the course of kidney disease. In some cases, early intervention can prevent further damage to the kidneys and improve long-term outcomes.